Preparation of Phthalyl Amlodipine_Kain Industrial Additives

background and overview[1] amlodipine, chemical name is 3-ethyl-5-methyl-2-(2-aminoethoxymethyl)-4-(-2-chlorophenyl)-6-methyl-1 , 4-dihydro-3,5-pyridinedicarboxylate, is a dihydropyridine calcium antagonist developed by pfizer in the united states in the 1990s. it is mainly used for the treatment of hypertension and angina pectoris as a treatment for hypertension. drug of choice, with sales ranking first among cardiovascular drugs in the world.…