Preparation of benzoylphenobarbital_Kain Industrial Additive

background and overview[1] benzophenobarbital (benzophenobarbital) is the prodrug of the sedative drug phenobarbital. compared with phenobarbital, it has the characteristics of less toxicity, less side effects, and lower dosage. there are few reports on the synthesis of benzoyl phenobarbital. literature reports use phenobarbital silver salt and benzoyl chloride to react and synthesize under catalyst-free conditions,…