Preparation of 4-(4-methylpiperazine)aniline_Kain Industrial Additives

background and overview[1] 4-(4-methylpiperazine)aniline can be used as a pharmaceutical intermediate. it can be prepared by reducing p-fluoronitrobenzene with n-methylpiperazine after nucleophilic substitution. 4-(4-methylpiperazine)aniline can be used to prepare 2-n-aryl-4-n-aryl-5-fluoropyrimidine compounds. this compound has a high fgfr4 inhibitory effect and can be used as an effective potential anticancer drug. fibroblast growth factor receptor (fgfr) is…