Preparation of 4-(4-hydroxyphenyl)butyric acid_Kain Industrial Additives

background 4-(4-hydroxyphenyl)butyric acid is an organic synthesis intermediate and pharmaceutical intermediate that can be used in laboratory research and development processes and chemical and pharmaceutical synthesis processes. preparation[1-2] method 1, step 1 4-(3-chloro-4-methoxyphenyl)-4-oxobutyric acid (131): alcl3 (7.78g, 57.4mmol) was dissolved in ch2cl2 (47 ml) was cooled to 0°c and 2-chloroanisole (5.00 g, 35.0 mmol) in…