Preparation of 3-bromo-4-aldehyde benzoic acid_Kain Industrial Additive

background and overview[1][2] 3-bromo-4-aldehyde benzoic acid is a white solid and an important pharmaceutical intermediate. the synthesis method reported in the literature is to use nbs to tetrabrominate two methyl groups from 2,5-dimethylbromobenzene as raw material, hydrolyze it into 2-bromoterephthalaldehyde, and disproportionate it to generate 3-bromo-4-( hydroxymethyl) benzoic acid, after oxidation, the target product 3-bromo-4-aldehyde…