Preparation of 2-chloro-5-cyanobenzene-1-sulfonyl chloride_Kain Industrial Additive

background and overview[1] 2-chloro-5-cyanobenzene-1-sulfonyl chloride is a phenyl cyanide derivative and can be used as a pharmaceutical synthesis intermediate. structure preparation[1] the preparation of 2-chloro-5-cyanobenzene-1-sulfonyl chloride is as follows: dissolve commercially available 4-chloro-3-benzonitrile in 4 parts of thf. to a portion of water, add sodium hydrosulfide (3 equiv.) and stir at 45 °c overnight. tlc…