preparation of 2-chloro-4-methylphenylboronic acid_kain industrial additive
background and overview[1] 2-chloro-4-methylbenzeneboronic acid can be used as a pharmaceutical synthesis intermediate and is often used as a raw material for coupling reactions such as suzuki. 2-chloro-4-methylbenzeneboronic acid can be prepared by reacting 2-chloro-4-methyl-1-iodobenzene with n-butyllithium. preparation[1] step 1: preparation of 2-chloro-4-methyl-1-iodobenzene concentrated sulfuric acid (80ml) was added to the stirring mixture of 2-chloro-4-methylaniline…

