preparation of 2-amino-4-[(4-fluorobenzyl)amino]-1-nitrobenzene_kain industrial additive
background and overview[1] 2-amino-4-[(4-fluorobenzyl)amino]-1-nitrobenzene can be used as a pharmaceutical synthesis intermediate. for example, retigabine is prepared, which is an anti-epileptic drug with multiple mechanisms such as a neuronal potassium channel opener and a gaba enhancer. the drug was developed by glaxosmithkline/valeant pharmaceuticals. it was approved for marketing in the eu on march 29, 2011…

