Preparation method of deuterated acetophenone_Kain Industrial Additive

overview[1] deuterated acetophenone is a deuterated reagent that can be prepared from benzene-d6 in two steps. preparation method[1] step 1: preparation of acetophenone-2′,3′,4′,5′,6′-d5(2). (reference: challacombe, k.; leach, se; plackett, sj; meakins, gdj chem.soc.perkin trans.1 1988,2213-2218.) in a 2l round bottom three-neck flask, a mechanical a stirrer, dropping funnel and reflux condenser connected to a gas…