Preparation method of 3-acetonitrilecyclobutylamine hydrochloride_Kain Industrial Additive

background and overview[1] 3-acetonitrilecyclobutylamine hydrochloride can be used as a pharmaceutical synthesis intermediate. preparation[1-2] method 1: 3-acetonitrilecyclobutylamine hydrochloride is prepared as follows: compound bb-30-1 (0.200g, 1.10mmol) was dissolved in dichloromethane (2ml), and then hydrogen chloride dioxane solution (1ml, 4m) was added. the reaction solution was stirred at 20°c for 2 hours. the reaction solution was…