Preparation method of 2-amino-3-fluorophenol_Kain Industrial Additive

background and overview 2-amino-3-fluorophenol is a phenol derivative and can be used as a pharmaceutical intermediate. preparation method[1-2] method 1, step 1 1-fluoro-3-methoxy-2-nitrobenzene: to a solution of 1,3-difluoro-2-nitrobenzene (100g, 0.63mol) in meoh (1.3l) at 0°c, slowly add meona solution (0.69mol, in meoh, composed of 15.9g metallic sodium and 200 ml meoh freshly prepared). the resulting…