Preparation and application of methyl 2-(tert-butoxy-2-carboxamide)-3-nitrobenzoate_Kain Industrial Additive

background and overview[1] methyl 2-(tert-butoxy-2-carboxamide)-3-nitrobenzoate is a pharmaceutical intermediate that can be used in the synthesis of candesartan. candesartan and candesartan cilexetil are a new type of non-peptide angiotensin ii (atii) receptor antagonist, which is clinically used for the treatment of hypertension. the drug was first launched in sweden in 1997. preparation[2] methyl 2-(tert-butoxy-2-carboxamide)-3-nitrobenzoate is…