Preparation and application of 3-bromo-2-fluorobenzonitrile_Kain Industrial Additive

background and overview[1] 3-bromo-2-fluorobenzonitrile is an organic intermediate that can be prepared from 3-bromo-2-fluorobenzoic acid in two steps. 3-bromo-2-fluorobenzonitrile can be used as a pharmaceutical intermediate for the preparation of stk4 inhibitors. preparation[1] step 1, preparation of 3-bromo-2-fluorobenzamide (2-80) 3-bromo-2-fluorobenzoic acid (2-79, 400 mg, 1.83 mmol) and socl2 (4.39 mg, 3.66 mmol) were dissolved in…