Application of p-methoxyaniline_Kain Industrial Additives

overview p-methoxyaniline is an important organic raw material that can be used to prepare a variety of pharmaceutical intermediates. apply[1-4] 1. clausenine is a carbazole natural product with antibacterial activity. cn201410027161 reports a copper-catalyzed reaction of 6-diazo-3-methyl-2-cyclohexen-1-one and p-methoxyaniline to generate 2-(4-methoxyphenylamino)-5- toluene; then through methylation and palladium-catalyzed c-c bond coupling, the natural product clausenine…