Application of 2-bromo-4-chloro-3-fluorobenzoic acid_Kain Industrial Additive

background and overview[1] 2-bromo-4-chloro-3-fluorobenzoic acid is an acid derivative that can be used as a pharmaceutical synthesis intermediate. preparation[1] 2-bromo-4-chloro-3-fluorobenzoic acid: a solution of 4-chloro-3-fluorobenzoic acid (2.0g, 11.46mmol) in thf (25ml) was passed through a syringe pump at -78°c for 30 minutes. add to a solution of lda (13.18 ml, 26.4 mmol) in thf (50…