6-dibromotoluene_Kain Industrial Additive

background and overview[1][2] 2,6-dibromotoluene can be obtained by bromination of p-nitrotoluene and can be used to prepare 2,6-dibromobenzyl. preparation[1] 1,3-dibromo-2-methyl-5-nitrobenzene: to a solution of 1-methyl-4-nitrobenzene (30.0g, 218.8mmol) in chcl3 (120ml), add iron powder (3.6g, 64.5mmol) and stir mechanically. then bromine (124.8g, 40ml, 780.9mmol) was slowly added while increasing the temperature to 40°c. after addition of…