preparation of 3,4,5-trimethoxybromobenzene_kain industrial additive

background and overview[1] 3,4,5-trimethoxybromobenzene can be used as a pharmaceutical synthesis intermediate. it can be prepared by the reaction of 5-bromo-1,2,3 trihydroxybenzene and dimethyl sulfate, or it can also be prepared from 4-bromo-2 , 6-dimethoxyphenol was prepared as the reaction raw material. preparation[1-2] option 1, cool the mixture of 5-bromo-1,2,3 trihydroxybenzene (1.3g, 5.63mmol), 1m naoh…

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