4S)-5-(biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid_Kain Industrial Additive

background and overview[1] (2r,4s)-5-(biphenyl-4-yl)-4-[(tert-butoxycarbonyl) amino]-2-methylpentanoic acid is a key intermediate in the preparation of sacubitril. sacubitril and valsartan can form the compound drug entresto at a ratio of 1:1. entresto is a first-in-class medicine developed by novartis to reduce the risk of cardiovascular death and hospitalization for heart failure and to reduce ejection fraction in…