4S)-3-hydroxy-4-phenyl-2-azetidinone_Kain Industrial Additive

background and overview[1] (3r,4s)-3-hydroxy-4-phenyl-2-azetidinone, referred to as (-)β-lactam, is a very potential chiral drug intermediate. there are two isomers, namely (3r, 4s) configuration and (3s, 4r). among them, the derivative of paclitaxel side chain c-13 of the (3r, 4s) configuration isomer is the most useful for preparing cancer clinical chemotherapy. an important chiral precursor of…