4-diphenyl-oxazacyclo-5-acid_Kain Industrial Additive

background and overview[1] 2,4-diphenyl-oxazacyclo-5-acid is a pharmaceutical intermediate that can be prepared in two steps from (2r,3s)-3-phenylisoserine and trimethyl orthobenzoate. get. it has been reported in the literature that 2,4-diphenyl-oxazacyclo-5-acid can be used to introduce substituents at the c-13 and c-14 positions of paclitaxel, retaining the ring skeleton and necessary functional groups of taxanes, and…