4-dichlorobenzamide_Kain Industrial Additives

background and overview[1] 2,4-dichlorobenzamide is a pharmaceutical intermediate that can be prepared from 2,4-dichlorobenzoic acid. preparation[1] method 1. preparation of a. 2,4-dichlorobenzoyl chloride in a 1000ml single-neck bottle, dissolve 2,4-dichlorobenzoic acid (100.0g, 523.5mmol) in dry tetrahydrofuran (200ml), add 4 drops of dry n,n-dimethylformamide, and chloride sulfoxide (93.4g, 785.3mmol). reflux reaction for 5 hours. after the…