4-dichloro-6-fluorobenzaldehyde_Kain Industrial Additive

background and overview[1] 2,4-dichloro-6-fluorobenzaldehyde can be used as a pharmaceutical synthesis intermediate. preparation[1] the preparation of 2,4-dichloro-6-fluorobenzaldehyde is as follows: to a solution of 1,3-dichloro-5-fluorobenzene (2.0g, 12mmol) in tetrahydrofuran (20ml) at -70°c, lithium diisopropylamide (2m solution in tetrahydrofuran, 18mmol) was added dropwise. 9.1ml). the reaction was stirred at -70 °c for 0.5 h, then n,n-dimethylformamide…