3S)-3-(benzoylamino)-2-hydroxyphenylpropionic acid ethyl ester_Kain Industrial Additive

background and overview[1] (2r, 3s)-3-(benzoylamino)-2-hydroxyphenylpropanoic acid ethyl ester is an important synthetic intermediate that can be used to synthesize the anti-cancer drug paclitaxel. the traditional synthesis method of (2r, 3s)-3-(benzoylamino)-2-hydroxyphenylpropionate ethyl ester mainly involves asymmetric dihydroxylation of α and β unsaturated esters, followed by azide substitution and reduction. be made of. preparation[1] 1) add 0.786g…