3]dioxole-4-carboxylic acid_Kain Industrial Additive

background and overview[1] 5-bromobenzo[1,3]dioxole-4-carboxylic acid can be used as a pharmaceutical synthesis intermediate. it can be prepared from 6-bromo-2,3-dihydroxybenzaldehyde in three steps. preparation[1] step 1: 6-bromo-2,3-dihydroxybenzaldehyde dissolve 6-bromo-2-hydroxy-3-methoxybenzaldehyde (2.00g, 8.65mmol) in dichloromethane (10ml) and cool to 0°c. boron tribromide (17.0 ml of a 1.0 m solution, 17.00 mmol) was added via syringe and the solution…