2-trifluoroethylamine_Kain Industrial Additive

background and overview[1] 1-phenyl-2,2,2-trifluoroethylamine can be used as a pharmaceutical synthesis intermediate. preparation[1] the preparation of 1-phenyl-2,2,2-trifluoroethylamine is as follows: synthesis of compound 4-b: dissolve 4-a (1.00g, 5.74mmol, 781.25ul, 1.00eq) in etoh (8.00ml) and water (4.00ml) at 25°c, then add hydroxylamine hydrochloride (598.31mg, 8.61mmol, 1.50 eq) and sodium acetate (941.70 mg, 11.48 mmol, 2.00 eq).…